How to perform a below-knee amputation
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Summary
Focus: Creation of a functional residual limb for prosthetic ambulation after irreversible damage to the distal lower extremity.
Key elements: Adequate bone length, proper stump shape, proximal nerve transection, secure vessel ligation, viable posterior muscle padding, and tension-free closure.
Indications and Clinical Context
General
Medical expert: Ville Vänni, trauma surgeon
Name of procedure: Below-knee amputation, below the knee amputation, transtibial amputation
Goal of Operation
Optimal stump length and shape with adequate viable muscle coverage and tension-free closure to enable healing and prosthetic function.
Problem
Irreversibly damaged distal leg tissue requiring removal, most commonly due to critical limb ischemia, diabetic foot sepsis, or severe trauma.
Diagnosis
Atherosclerosis of native arteries of extremities (ICD-10: I70.2)
Type 2 diabetes with peripheral angiopathy (ICD-10: E11.5)
Type 1 diabetes with peripheral angiopathy (ICD-10: E10.5)
Osteomyelitis (ICD-10: M86.6)
No-pressure chronic ulcer of lower limb (ICD-10: L97)
Traumatic amputation of lower leg (ICD-10: S88)
Malignant neoplasm of bone and articular cartilage of lower limb (ICD-10: C40.2)
Short Pathophysiological Description
Despite diverse etiologies, all indications share a common endpoint: irreversibly damaged tissue that threatens limb viability. Whether from vascular insufficiency, uncontrolled infection, or tumor invasion, the affected tissue cannot heal and becomes a source of ongoing complications.
Key Anatomical Structures
Tibia
Tibial tuberosity
Fibula
Anterior compartment
Deep peroneal nerve
Anterior tibial artery and veins
Lateral compartment
Superficial peroneal nerve
Deep posterior compartment
Tibial nerve
Posterior tibial artery and veins
Peroneal artery and veins
Superficial posterior compartment
Soleus
Gastrocnemius
Subcutaneous neurovasculars
Great saphenous vein
Saphenous nerve
Small saphenous vein
Sural nerve
Step-by-Step Technique
Procedure Goal and Anatomical Strategy
The goal of this procedure is to create a functional residual limb for prosthetic ambulation after irreversible damage to the distal lower extremity from vascular disease, severe trauma, tumor, or aggressive infection.
Achieving this depends on adequate bone length, proper stump shape, appropriate nerve end management, and well-vascularized muscle padding with proper wound positioning and healing capable of withstanding lifelong loading.
The procedure addresses the leg's four compartments in sequence from anterior to posterior. The anterior, lateral, and deep posterior compartments require managing their neurovascular structures—transecting nerves proximally to prevent neuromas and ligating arteries and veins for hemorrhage control. The superficial posterior compartment forms the posterior flap, with gastrocnemius forming the majority. The flap is thinned to avoid excessive bulk while preserving sufficient tissue to compensate for inevitable postoperative muscle atrophy.
Patient Positioning, Anesthesia, and Preparation
The patient is positioned supine with the lower limb exposed to the groin level and prepared in a sterile fashion.
The procedure can be performed under spinal or general anesthesia depending on patient factors.
A thigh tourniquet is applied when appropriate to reduce bleeding and provide a clear operative field. Tourniquet use is avoided in patients with severe arteriosclerosis and heavily calcified femoral arteries, as it may cause plaque rupture or fail to adequately occlude the vessels.
Determining Amputation Level and Planning Incisions
The amputation level is primarily determined by the extent of pathology—whether vascular, soft tissue, or bone injury. The decision must balance achieving the most distal amputation possible while removing all compromised tissue and respecting certain biomechanical and technical boundaries.
Proximally, the critical constraint is preserving adequate bone length. A minimum of 7 centimeters of bone must remain distal to the knee joint line to allow prosthetic socket attachment and maintain thigh muscle function.
In practice, the tibial tuberosity serves as a palpable landmark, with typical levels falling 10 to 12 centimeters below it.Distally, sufficient space must remain for prosthetic ankle components. At least 17 centimeters from the floor to the bone section level is required to accommodate the typical prosthetic components.
Additionally, with the posterior flap technique, the amputation level must not extend beyond where the posterior superficial compartment muscles transition to tendon, as the posterior flap will be rotated anteriorly to cover the bone ends and requires viable muscle tissue for vascularity and padding.
Once the amputation level is determined based on pathology extent and the relevant proximal or distal constraints, the transverse anterior incision is marked at that level across the front of the leg.
On the sides, this line curves slightly posteriorly and proximally to minimize dog ears and facilitate easier closure.The fibula is palpated to guide the lateral extent of the transverse incision and placement of the longitudinal incision, ensuring access to the lateral compartment.
The longitudinal incision extends distally along the fibula toward the lateral malleolus, with final length determined when fitting the posterior flap.Then the medial longitudinal incision is marked, curving similarly and positioned to leave approximately one-third of the leg circumference posteriorly for the flap that will provide coverage.
The exact transection level of the posterior flap will be determined after the bones are divided.
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Skin Incision and Advancing to Fascia
Following the planned transverse incision, the skin and subcutaneous tissue are incised with a scalpel to the fascia surface level.
The lateral longitudinal incision is made with the same technique, advancing through the skin and subcutis following the traced plan. The fascia should be visible throughout the full incision length.
The medial longitudinal incision is made similarly. Care is taken to identify and preserve the great saphenous vein and saphenous nerve, which run along the medial aspect of the leg.
The great saphenous vein is identified in the subcutaneous tissue along the medial incision.
The vein is clamped distally and proximally, and then divided. Both ends of the vessel are ligated.
The saphenous nerve is identified near the great saphenous vein.
The nerve is isolated and sharply transected proximally to allow retraction away from the surgical site.
With the fascia exposed along all incision lines, the underlying muscle compartments are now accessible.
Dividing the Anterior Compartment
To expose the tibia and fibula for transection, both the anterior and lateral compartments are divided with their neurovascular structures managed. The anterior compartment is addressed first, with its anterior tibial vessels and deep peroneal nerve handled.
The fascia of the anterior compartment is incised at the planned amputation level.
The anterior compartment muscles are first separated from the lateral compartment along the anterior intermuscular septum, then freed from the tibia medially.
The muscles are then bluntly encircled while carefully excluding the neurovascular bundle at the base of the compartment, just anterior to the interosseous membrane.
The encircled muscles are divided sharply at the amputation level. With the tourniquet in use, bleeding from the muscle is minimal.
The neurovascular bundle of the anterior compartment is identified at the base of the compartment. This bundle contains the anterior tibial artery, the anterior tibial veins, and the deep peroneal nerve.
The deep peroneal nerve is identified, separated from the vessels, and divided sharply at proximal level.
The anterior tibial artery is isolated, clamped proximally and distally, and then divided. The artery and its accompanying veins should be ligated separately to prevent arteriovenous fistula formation.
To ensure secure ligation and prevent the ligature from slipping off, a transfixion suture is placed through and around the proximal end of the artery. A second ligature can be placed proximally to this for additional security.
The distal end of the artery is ligated with a simple suture.
Complete division of the anterior compartment is confirmed by visualization of the interosseous membrane at the compartment floor.
Dividing the Lateral Compartment
The lateral compartment along the fibula contains the superficial peroneal nerve requiring transection, but not the peroneal artery, which lies in the deep posterior compartment and will be managed after the bone cuts.
The compartment is encircled with a finger.
The muscles are divided sharply at the amputation level until the superficial peroneal nerve appears.
The nerve is identified, isolated, and sharply transected proximally to allow retraction away from the stump. Anesthetic will be applied later.
The remaining lateral compartment muscles are divided completely.
With the anterior and lateral compartments divided, both the tibia and fibula are now visible and ready to be prepared for cutting.
Bone Transection
To achieve the planned limb length, the tibia is cut at the determined level and the fibula slightly more proximally. To enable safe transection, the tibia and fibula are first encircled and freed from surrounding tissues.
The interosseous membrane connecting the tibia and fibula is identified at the bottom of the anterior compartment.
The membrane is incised with a scalpel at the planned amputation level to allow the tibia to be encircled and cut.
The deep posterior compartment behind the membrane, containing the major vessels and tibial nerve, is not accessed now but will be addressed after the distal leg has been separated.The tibia is encircled with Crile forceps along the bone surface, passed both laterally and medially, to separate the bone from adjacent tissues and enable retractor placement.
The anterior periosteum is freed from the tibia for a few centimeters proximally; this area will be beveled later.
The fibula cut level is planned approximately 1 to 2 centimeters proximal to the tibial cut level. This prevents the fibula from creating a prominent distal point that could cause pressure issues with the prosthesis.
Using the same technique as for the tibia, Crile forceps encircle the fibula and the periosteum is elevated at the cut site.
Retractors are placed to protect the adjacent soft tissues during bone cutting.
A final assessment confirms that this cut level will position the anterior closure line appropriately on the stump.
The tibia is cut transversely with an oscillating saw at the planned level.
The fibula is cut with the same technique at the more proximal level. Similarly, retractors are positioned to protect the soft tissues.
With the bones cut at appropriate levels, the posterior structures can be addressed next to complete the amputation.
Posterior Flap Detachment and Distal Limb Removal
The objective is to detach the posterior soft tissues from the bones and remove the distal leg, leaving an initial posterior flap of adequate length for bone coverage.
The fascia is opened along the lateral and medial vertical incisions to allow the distal bones to be mobilized.
The distal tibia and fibula are lifted and reflected forward.
The posterior muscles are sharply detached from the posterior aspects of the bones, staying directly on the bone surface to avoid injuring the major posterior arteries. Small perforating vessels between compartments are clamped as needed, and any major venous bleeding is ligated.
The dissection continues distally posterior to the bones down to the level defined by the skin incisions.
The posterior flap length is assessed to ensure adequate coverage for the tibial bone end without tension. The flap will be thinned and shaped more later.
At this point, the posterior flap includes both superficial and deep posterior compartment muscles. With tourniquet control, the flap can be transected sharply with the vascular structures in the deep compartment ligated afterward. Alternatively, the major arteries could be controlled and ligated before transection.
As the posterior flap is transected at the determined level, the distal leg is separated, leaving adequate length of the posterior tissue for tension-free bone coverage.
Managing Neurovasculars and Dividing the Deep Posterior Compartment
The next step is to manage the nerves and vessels of the flap to achieve reliable hemostasis while maintaining flap viability and to create a pain-free stump. The deep posterior compartment contains the tibialis posterior and toe flexor muscles. Between the toe flexor muscles lie the major neurovascular structures: the tibial nerve and the posterior tibial vessels, along with the peroneal vessels.
The tibial nerve is located in the deep posterior compartment. Being the thickest nerve in the lower leg, identification is typically straightforward.
The nerve is carefully exposed without excessive tension.
Sharp transection of the nerve is done at an appropriate proximal level to allow the nerve ending to retract away from the weight-bearing surface of the stump. Anesthetic can be applied at the time of transection, or pain control managed later.
Then the plane separating the deep posterior compartment from the superficial posterior compartment is identified.
The compartments are separated along this avascular plane.
The deep compartment muscles are removed to reduce the bulk of the stump by transecting them at the amputation level.
The superficial posterior compartment contains the gastrocnemius and soleus muscles, with the gastrocnemius forming the majority of the flap and receiving its blood supply from the popliteal artery above the amputation level, ensuring continued flap viability.
The posterior tibial and peroneal vessels are identified in the deep compartment, running surprisingly close to each other.
Crile forceps are applied for temporary control.
Both main arterial trunks are secured with transfixion suture ligatures to prevent slippage and delayed bleeding. Double ligation can be performed on the arteries. The veins can be ligated separately to prevent arteriovenous fistula formation.
Bone End Beveling and Preparation
The bone ends are prepared to prevent irritation of the overlying soft tissues.
The fibula is confirmed to be cut 1 to 2 centimeters more proximally than the tibia to prevent skin irritation from the longer bone end.
The anterior edge of the tibia is beveled with the saw to create an oblique surface. The soft tissues are protected with retractors during sawing.
Any sharp edges are filed smooth to create a rounded bone surface suitable for weight-bearing.
The medullary canal can be evacuated and bone wax applied if bleeding is significant.
Posterior Flap Trimming and Shaping
The goal of this step is to achieve optimal muscle coverage of the bone stump to ensure adequate healing. Excessive bulk would interfere with prosthesis fitting, while closure under tension would compromise wound healing. It is important to note that the stump should not be thinned to an optimal-looking result at this point but should appear somewhat bulky, since muscle will atrophy significantly postoperatively.
The posterior flap is fitted over the bone stump to assess how much soft tissue is required for closure and to determine the appropriate flap length without tension.
Before transecting the muscle layer, the sural nerve is identified posteriorly and divided sharply. The accompanying small saphenous vein is ligated if not already done at this stage.
The posterior flap is then transected at the determined length.
Small intramuscular vessels should be cauterized to reduce bleeding when the tourniquet is released. However, excessive cauterization should be avoided to preserve tissue viability.
The corners of the flap are trimmed and rounded to improve the fit and shape.
Then the challenging work of determining the optimal muscle volume begins. Muscle is removed gradually with evaluation after each trimming.
The muscle volume achieved here affects bone coverage, stump shape for prosthesis use, and wound healing success. The muscle tissue must look vital with healthy appearance and bleeding surface to heal properly. Any non-viable tissue must be removed.While reducing muscle volume, the subcutaneous tissue and skin length must be evaluated to ensure adequate length for tension-free closure.
In this case, there is an adequate amount of soft tissue to cover the stump without tension.
The stump appears slightly mushroom-shaped initially, but it will slim considerably with atrophy and the help of compressive bandages. If made too neat now, it becomes tapered and too thin later.To further facilitate closure, the posterior fascia can be dissected slightly from the posterior subcutaneous flap. The dissection should not be so extensive that the skin flap becomes devascularized, but enough to allow better muscle fitting.
The flap now fits well over the bone stump with vital muscle tissue and minimal tension, providing adequate coverage without overly excessive bulk.
If excess subcutaneous tissue and skin remain at this point, they can be trimmed later.
Anesthesia and Hemostasis
The locations of the nerve trunks are confirmed and, if not already applied at the time of transection, anesthetic is administered at the nerve transection sites.
A pain catheter can be inserted along the tibial nerve trunk for continued postoperative pain control.
The tourniquet is then released, and complete hemostasis is ensured. Remaining bleeders are cauterized or ligated as needed. Some diffuse muscle oozing is acceptable, as it typically stops when the muscles are approximated, avoiding excessive cauterization that could impair healing.
Drain placement is controversial. It prevents hematoma when hemostasis is suboptimal but may interfere with pain catheter function. If no drain is used, bone wax can seal the medullary canal to prevent deep hematoma.
Muscle and Fascial Closure
The goal is to secure the posterior muscle flap over the bone stump by suturing the posterior fascia to the anterior fascia edge, ensuring secure coverage without excessive tension that might compromise tissue perfusion.
Interrupted sutures are placed using size 0 or 1 absorbable suture. The bites are taken from the posterior fascia to the thick, sturdy anterior fascia edge.
The sutures are first placed sparsely to evaluate stump formation and tissue alignment.
If the closure appears too tight, the tissues are misaligned, or the flap does not settle properly over the bone stump, individual sutures can be removed and repositioned.Here, the flap conforms nicely to the bone stump without tension and the overall appearance and alignment are acceptable.
Additional sutures can be placed to approximate any gaping areas.
When the posterior and anterior fascial layers are securely opposed throughout the length of the wound without gaps or excessive tension, subcutaneous and skin closure can proceed.
Subcutaneous Closure
Depending on the thickness of the subcutaneous layer, few sutures can be applied to shape the tissue and set up for optimal skin approximation. A watertight subcutaneous closure should be avoided, as this could compromise flap perfusion and cause ischemia.
In this case, few interrupted sutures using inverted mattress technique with size 2-0 absorbable suture are placed.
If needed, excess subcutaneous tissue and skin can be removed at this stage, generally from the posterior flap, which is mobile, rather than the anterior side, which is fixed to the compartment and tibia.
Subcutaneous closure is adequate when the skin edges can be approximated without tension, no apparent dog ears will form, and no further deep adjustments are required.
Skin Closure
Skin closure starts with first placing few interrupted nylon sutures sparsely to align the anterior and posterior flap. This prevents misalignment that could occur if stapling proceeds from one end to the other. Excess skin could still be trimmed at this stage if dog ears would form.
Once it seems that the flaps will align nicely, rapid closure with staples can be done.
The staples are applied at intervals of approximately 1 centimeter or a bit less, balancing secure closure with preservation of wound edge perfusion.
Initially, the appearance of the stump often remains slightly bulky and mushroom-shaped, which is appropriate. If thinned excessively at this point, the stump will become atrophic as muscle atrophies significantly after surgery.
To mold the stump into adequate shape for prosthesis fitting, compressive dressing is essential for the next weeks. The dressing also takes the pressure off the suture line.
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Piftalls and Complications
Pitfalls
Incorrect Amputation Level/Incision Site
Planning the incision too distally or at the wrong level can lead to inadequate tissue coverage, poor wound healing, and poorly fitting prosthesis. The amputation level must balance pathology removal with preserving adequate proximal bone length while respecting distal prosthetic space requirements and sufficient tissue with adequate perfusion for closure and healing.
Too short skin flaps may result in tension in wound closure and subsequent problems in healing, such as dehiscence, necrosis, or infection, limb contraction, or prosthesis fitting. The posterior flap is therefore initially left long, with final length determined when fitting it over the bone ends.
Inadequate Nerve End Management
If the tibial nerve, deep peroneal nerve, superficial peroneal nerve, sural nerve, and saphenous nerve are not transected at an appropriate proximal level, they can form neuromas causing stump sensitivity and chronic pain. The nerves should be divided proximally enough that the cut ends retract away from weight-bearing and pressure areas of the stump.
Improper Posterior Flap Trimming
Muscle atrophy after amputation is typically significant, making volume assessment of the posterior flap critical. Excessive trimming of the muscle volume creates an optimal appearance intraoperatively but results in a cone-shaped stump with inadequate padding after atrophy, causing poor prosthetic fit. Conversely, insufficient trimming produces a bulbous stump that delays prosthetic fitting.
Careless Hemostasis
Proceeding hastily without meticulous hemostasis can lead to significant bleeding, especially in patients on anticoagulants or with coagulation disorders. Failure to carefully ligate the anterior tibial vessels, posterior tibial vessels, and peroneal vessels can cause massive bleeding and hematoma formation.
Closure Under Excessive Tension
Forcing tissues together too tightly can cause tissue ischemia and compromise wound healing capacity. Closure should approximate the wound edges with minimal tension.
Complications
Postoperative Hemorrhage
The major vessels of the lower leg—anterior tibial, posterior tibial, and peroneal arteries and veins—should be carefully identified and ligated with transfixing ligature and preferably with double ligation. Meticulous hemostasis of all perforating branches throughout the procedure should be done.
Neuroma Formation
All encountered nerves—saphenous nerve, deep peroneal nerve, superficial peroneal nerve, tibial nerve, and sural nerve—should be transected at an appropriate proximal level using sharp division, allowing the cut ends to retract away from weight-bearing and pressure areas of the stump. Nerves should not be incorporated into suture lines or scar tissue.
Bone Protrusion Through Stump
Bone edges should be beveled, especially the anterior tibia, and bone ends filed smooth to eliminate sharp angles. There should be adequate soft tissue coverage relative to bone length.
Wound Dehiscence
The incision should be planned at an appropriate level, ensuring adequate tissue for closure without forcing edges together.
Tension-free closure is achieved with appropriate suture spacing.
Skin Flap Necrosis
Dissection between the skin/subcutaneous tissue and the muscular fascia of the posterior flap should be minimized to preserve perforating vessels.
Closure of superficial layers should be performed without tension.
Inadequate Bone Padding (Cone-Shaped Stump)
Excessive thinning of the posterior flap leads to cone-shaped stump formation after muscle atrophy. The flap should be thinned to avoid excessive bulk but maintain sufficient volume to account for inevitable postoperative muscle atrophy.
Hip Flexion Contracture
To maintain hip joint mobility, early mobilization postoperatively is important. Prolonged hip flexion positioning during bed rest should be avoided. Early achievement of horizontal hip position is encouraged.
Aftercare
General Guidelines
A soft, compressive dressing is applied. The process of developing a fitting prosthesis starts after the removal of skin sutures/staples, at approximately 2 to 4 weeks postoperatively.
Sufficient pain management is essential and may prevent phantom limb pain.
FAQ
What is the goal of below-knee amputation?
The goal is to create a functional residual limb for prosthetic ambulation, with optimal stump length and shape, adequate viable muscle coverage, and tension-free closure to enable healing and prosthetic function.
How is the amputation level determined?
The amputation level is primarily determined by the extent of vascular, soft tissue, or bone pathology, while balancing removal of all compromised tissue with preservation of adequate proximal bone length, distal prosthetic space requirements, and sufficient viable tissue for closure.
Why is the posterior flap not thinned to an optimal-looking result during surgery?
The stump should appear somewhat bulky initially because muscle atrophy after amputation is significant; excessive intraoperative thinning can later result in a tapered, cone-shaped stump with inadequate padding.
Which nerves require proximal transection?
The tibial nerve, deep peroneal nerve, superficial peroneal nerve, sural nerve, and saphenous nerve should be transected at an appropriate proximal level so the cut ends retract away from weight-bearing and pressure areas of the stump.
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